While antibiotics have reduced the global burden of infectious disease, these miracle drugs are no longer working against emerging “superbugs.” A recent report from the UK estimates that, by 2050, nearly 10 million people are likely to die from drug-resistant infections if the current trends persist. In response, Professor Elena Ivanova and her team have generated bactericidal surfaces that physically rupture bacterial cells in a few hundred seconds without harming animal cells. The rapidness with which they kill ensures that there is little opportunity for bacteria to adapt and become resistant. In the middle of a global antimicrobial resistance crisis, Professor Ivanova’s work provides hope that we haven’t yet lost the fight against superbugs!